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782475-37-0

782475-37-0 structure
782475-37-0 structure
  • Name: Br-PEG3-C2-Boc
  • Chemical Name: 2-Methyl-2-propanyl 3-{2-[2-(2-bromoethoxy)ethoxy]ethoxy}propanoate
  • CAS Number: 782475-37-0
  • Molecular Formula: C13H25BrO5
  • Molecular Weight: 341.239
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-16 16:56:50
  • Modify Date: 2024-01-10 12:11:48
  • Br-PEG3-C2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name 2-Methyl-2-propanyl 3-{2-[2-(2-bromoethoxy)ethoxy]ethoxy}propanoate
Synonyms 2-Methyl-2-propanyl 3-{2-[2-(2-bromoethoxy)ethoxy]ethoxy}propanoate
Propanoic acid, 3-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
Description Br-PEG3-C2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.2±0.1 g/cm3
Boiling Point 375.4±27.0 °C at 760 mmHg
Molecular Formula C13H25BrO5
Molecular Weight 341.239
Flash Point 180.8±23.7 °C
Exact Mass 340.088531
LogP 1.68
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.464
Hazard Codes Xi
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