936917-36-1

936917-36-1 structure

Name: Iodo-PEG4-N3
Chemical Name: 1-Azido-2-{2-[2-(2-iodoethoxy)ethoxy]ethoxy}ethane
CAS Number: 936917-36-1
Molecular Formula: C₈H₁₆IN₃O₃
Molecular Weight: 329.135
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-07-20 12:49:09
Modify Date: 2024-01-10 15:19:22
Iodo-PEG4-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	1-Azido-2-{2-[2-(2-iodoethoxy)ethoxy]ethoxy}ethane
Synonyms	Ethane, 1-(2-azidoethoxy)-2-[2-(2-iodoethoxy)ethoxy]- 1-Azido-2-{2-[2-(2-iodoethoxy)ethoxy]ethoxy}ethane

Description	Iodo-PEG4-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562