Iodo-PEG4-N3

Modify Date: 2024-01-10 15:19:22

Iodo-PEG4-N3 Structure
Iodo-PEG4-N3 structure
Common Name Iodo-PEG4-N3
CAS Number 936917-36-1 Molecular Weight 329.135
Density N/A Boiling Point N/A
Molecular Formula C8H16IN3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Iodo-PEG4-N3


Iodo-PEG4-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1-Azido-2-{2-[2-(2-iodoethoxy)ethoxy]ethoxy}ethane
Synonym More Synonyms

 Iodo-PEG4-N3 Biological Activity

Description Iodo-PEG4-N3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C8H16IN3O3
Molecular Weight 329.135
Exact Mass 329.023621
LogP 0.81

 Synonyms

Ethane, 1-(2-azidoethoxy)-2-[2-(2-iodoethoxy)ethoxy]-
1-Azido-2-{2-[2-(2-iodoethoxy)ethoxy]ethoxy}ethane