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125220-94-2

125220-94-2 structure
125220-94-2 structure
  • Name: m-PEG-acid
  • Chemical Name: 2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaoctatriacontan-38-oic acid
  • CAS Number: 125220-94-2
  • Molecular Formula: (C2H4O)nC4H8O3
  • Molecular Weight: 588.683
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-14 03:55:28
  • Modify Date: 2025-08-25 09:18:14
  • m-PEG-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaoctatriacontan-38-oic acid
Synonyms MFCD08274611
2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaoctatriacontan-38-oic acid
Description m-PEG-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Density 1.1±0.1 g/cm3
Boiling Point 628.8±55.0 °C at 760 mmHg
Molecular Formula (C2H4O)nC4H8O3
Molecular Weight 588.683
Flash Point 189.3±25.0 °C
Exact Mass 588.335693
LogP -4.22
Vapour Pressure 0.0±4.0 mmHg at 25°C
Index of Refraction 1.461
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