m-PEG-acid

Modify Date: 2024-01-06 01:24:52

m-PEG-acid Structure
m-PEG-acid structure
Common Name m-PEG-acid
CAS Number 125220-94-2 Molecular Weight 588.683
Density 1.1±0.1 g/cm3 Boiling Point 628.8±55.0 °C at 760 mmHg
Molecular Formula (C2H4O)nC4H8O3 Melting Point N/A
MSDS N/A Flash Point 189.3±25.0 °C

 Use of m-PEG-acid


m-PEG-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaoctatriacontan-38-oic acid
Synonym More Synonyms

 m-PEG-acid Biological Activity

Description m-PEG-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 628.8±55.0 °C at 760 mmHg
Molecular Formula (C2H4O)nC4H8O3
Molecular Weight 588.683
Flash Point 189.3±25.0 °C
Exact Mass 588.335693
LogP -4.22
Vapour Pressure 0.0±4.0 mmHg at 25°C
Index of Refraction 1.461

 Synonyms

MFCD08274611
2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaoctatriacontan-38-oic acid
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