134179-40-1
134179-40-1 structure
- Name: TBDMS-PEG4-OH
- Chemical Name: 2,2,3,3-Tetramethyl-4,7,10,13-tetraoxa-3-silapentadecan-15-ol
- CAS Number: 134179-40-1
- Molecular Formula: C14H32O5Si
- Molecular Weight: 308.486
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-05 20:37:13
- Modify Date: 2025-08-25 19:20:40
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TBDMS-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2,2,3,3-Tetramethyl-4,7,10,13-tetraoxa-3-silapentadecan-15-ol |
|---|---|
| Synonyms |
2,2,3,3-Tetramethyl-4,7,10,13-tetraoxa-3-silapentadecan-15-ol
4,7,10,13-Tetraoxa-3-silapentadecan-15-ol, 2,2,3,3-tetramethyl- MFCD25424114 |
| Description | TBDMS-PEG4-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 349.6±27.0 °C at 760 mmHg |
| Molecular Formula | C14H32O5Si |
| Molecular Weight | 308.486 |
| Flash Point | 165.2±23.7 °C |
| Exact Mass | 308.201904 |
| LogP | 1.42 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.441 |