956494-20-5

956494-20-5 structure

Name: Biotin-PEG11-azide
Chemical Name: 2-Methyl-2-propanyl (17-azido-3,6,9,12,15-pentaoxaheptadec-1-yl)carbamate
CAS Number: 956494-20-5
Molecular Formula: C₁₇H₃₄N₄O₇
Molecular Weight: 406.474
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-07-03 04:34:23
Modify Date: 2024-01-04 07:13:52
Biotin-PEG-azide (MW 1000) is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1].

Name	2-Methyl-2-propanyl (17-azido-3,6,9,12,15-pentaoxaheptadec-1-yl)carbamate
Synonyms	Carbamic acid, N-(17-azido-3,6,9,12,15-pentaoxaheptadec-1-yl)-, 1,1-dimethylethyl ester 2-Methyl-2-propanyl (17-azido-3,6,9,12,15-pentaoxaheptadec-1-yl)carbamate

Description	Biotin-PEG-azide (MW 1000) is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs[1]
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein[1]. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.