Biotin-PEG11-azide

Modify Date: 2024-01-04 07:13:52

Biotin-PEG11-azide Structure
Biotin-PEG11-azide structure
Common Name Biotin-PEG11-azide
CAS Number 956494-20-5 Molecular Weight 406.474
Density N/A Boiling Point N/A
Molecular Formula C17H34N4O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotin-PEG11-azide


Biotin-PEG-azide (MW 1000) is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1].

 Names

Name 2-Methyl-2-propanyl (17-azido-3,6,9,12,15-pentaoxaheptadec-1-yl)carbamate
Synonym More Synonyms

 Biotin-PEG11-azide Biological Activity

Description Biotin-PEG-azide (MW 1000) is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1].
Related Catalog
Target

PEGs[1]

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein[1]. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C17H34N4O7
Molecular Weight 406.474
Exact Mass 406.242737
LogP -0.02

 Synonyms

Carbamic acid, N-(17-azido-3,6,9,12,15-pentaoxaheptadec-1-yl)-, 1,1-dimethylethyl ester
2-Methyl-2-propanyl (17-azido-3,6,9,12,15-pentaoxaheptadec-1-yl)carbamate
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