444020-69-3

444020-69-3 structure

Name: 3’-Deoxy-3’-α-C-methylguanosine
Chemical Name: 3'-Deoxy-3'-methylguanosine
CAS Number: 444020-69-3
Molecular Formula: C₁₁H₁₅N₅O₄
Molecular Weight: 281.27
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-06-24 15:44:24
Modify Date: 2024-01-08 11:47:38
3’-Deoxy-3’-α-C-methylguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	3'-Deoxy-3'-methylguanosine
Synonyms	3'-Deoxy-3'-methylguanosine Guanosine, 3'-deoxy-3'-methyl-

Description	3’-Deoxy-3’-α-C-methylguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.