3’-Deoxy-3’-α-C-methylguanosine

Modify Date: 2024-01-08 11:47:38

3’-Deoxy-3’-α-C-methylguanosine Structure
3’-Deoxy-3’-α-C-methylguanosine structure
Common Name 3’-Deoxy-3’-α-C-methylguanosine
CAS Number 444020-69-3 Molecular Weight 281.27
Density 2.0±0.1 g/cm3 Boiling Point N/A
Molecular Formula C11H15N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3’-Deoxy-3’-α-C-methylguanosine


3’-Deoxy-3’-α-C-methylguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 3'-Deoxy-3'-methylguanosine
Synonym More Synonyms

 3’-Deoxy-3’-α-C-methylguanosine Biological Activity

Description 3’-Deoxy-3’-α-C-methylguanosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 2.0±0.1 g/cm3
Molecular Formula C11H15N5O4
Molecular Weight 281.27
Exact Mass 281.112396
LogP -0.23
Index of Refraction 1.856

 Synonyms

3'-Deoxy-3'-methylguanosine
Guanosine, 3'-deoxy-3'-methyl-
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