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1807512-47-5

1807512-47-5 structure
1807512-47-5 structure
  • Name: Mal-PEG2-PFP ester
  • Chemical Name: Pentafluorophenyl 3-{2-[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy}propanoate
  • CAS Number: 1807512-47-5
  • Molecular Formula: C17H14F5NO6
  • Molecular Weight: 423.288
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-03 14:55:34
  • Modify Date: 2024-01-22 19:29:21
  • Mal-PEG2-PFP ester is a Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.

Name Pentafluorophenyl 3-{2-[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy}propanoate
Synonyms Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester
Pentafluorophenyl 3-{2-[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy}propanoate
Description Mal-PEG2-PFP ester is a Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Density 1.5±0.1 g/cm3
Boiling Point 493.1±45.0 °C at 760 mmHg
Molecular Formula C17H14F5NO6
Molecular Weight 423.288
Flash Point 252.0±28.7 °C
Exact Mass 423.074127
LogP 2.00
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.501