Mal-PEG2-PFP ester

Modify Date: 2024-01-22 19:29:21

Mal-PEG2-PFP ester Structure
Mal-PEG2-PFP ester structure
Common Name Mal-PEG2-PFP ester
CAS Number 1807512-47-5 Molecular Weight 423.288
Density 1.5±0.1 g/cm3 Boiling Point 493.1±45.0 °C at 760 mmHg
Molecular Formula C17H14F5NO6 Melting Point N/A
MSDS N/A Flash Point 252.0±28.7 °C

 Use of Mal-PEG2-PFP ester


Mal-PEG2-PFP ester is a Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.

 Names

Name Pentafluorophenyl 3-{2-[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy}propanoate
Synonym More Synonyms

 Mal-PEG2-PFP ester Biological Activity

Description Mal-PEG2-PFP ester is a Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 493.1±45.0 °C at 760 mmHg
Molecular Formula C17H14F5NO6
Molecular Weight 423.288
Flash Point 252.0±28.7 °C
Exact Mass 423.074127
LogP 2.00
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.501

 Synonyms

Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester
Pentafluorophenyl 3-{2-[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy}propanoate
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