1217094-53-5

1217094-53-5 structure

Name: ICI-118551
Chemical Name: ICI-118551
CAS Number: 1217094-53-5
Molecular Formula: C₁₇H₂₈ClNO₂
Molecular Weight: 313.86
Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
Create Date: 2018-06-16 09:03:53
Modify Date: 2024-01-02 15:55:03
(Rac)-ICI-118551 hydrochloride is a selective β2-adrenergic receptor antagonist. (Rac)-ICI-118551 hydrochloride can inhibit dendrite ramification of hippocampal neurons in a mouse model of Alzheimer's disease[1].

Name	ICI-118551
Synonyms	3-(Isopropylamino)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-2-butanol hydrochloride (1:1) MFCD00153812 2-Butanol, 1-[(2,3-dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-, hydrochloride (1:1) 3-(Isopropylamino)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]butan-2-ol hydrochloride (1:1) ICI-118551 HYDROCHLORIDE

Description	(Rac)-ICI-118551 hydrochloride is a selective β2-adrenergic receptor antagonist. (Rac)-ICI-118551 hydrochloride can inhibit dendrite ramification of hippocampal neurons in a mouse model of Alzheimer's disease[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Neurological Disease
References	[1]. Wu Q, et, al. Blocking beta 2-adrenergic receptor inhibits dendrite ramification in a mouse model of Alzheimer's disease. Neural Regen Res. 2017 Sep;12(9):1499-1506.