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1367918-21-5

1367918-21-5 structure
1367918-21-5 structure
  • Name: Methylamino-PEG1-acid HCl
  • Chemical Name: Methylamino-PEG1-acid
  • CAS Number: 1367918-21-5
  • Molecular Formula: C6H13NO3
  • Molecular Weight: 147.172
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-08 11:27:05
  • Modify Date: 2024-01-23 10:17:22
  • Methylamino-PEG1-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Methylamino-PEG1-acid
Synonyms MFCD26783686
Description Methylamino-PEG1-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 253.9±20.0 °C at 760 mmHg
Molecular Formula C6H13NO3
Molecular Weight 147.172
Flash Point 107.3±21.8 °C
Exact Mass 147.089539
LogP -0.54
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.448