Methylamino-PEG1-acid HCl

Modify Date: 2024-01-23 10:17:22

Methylamino-PEG1-acid HCl Structure
Methylamino-PEG1-acid HCl structure
Common Name Methylamino-PEG1-acid HCl
CAS Number 1367918-21-5 Molecular Weight 147.172
Density 1.1±0.1 g/cm3 Boiling Point 253.9±20.0 °C at 760 mmHg
Molecular Formula C6H13NO3 Melting Point N/A
MSDS N/A Flash Point 107.3±21.8 °C

 Use of Methylamino-PEG1-acid HCl


Methylamino-PEG1-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Methylamino-PEG1-acid
Synonym More Synonyms

 Methylamino-PEG1-acid HCl Biological Activity

Description Methylamino-PEG1-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 253.9±20.0 °C at 760 mmHg
Molecular Formula C6H13NO3
Molecular Weight 147.172
Flash Point 107.3±21.8 °C
Exact Mass 147.089539
LogP -0.54
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.448

 Synonyms

MFCD26783686