1381861-91-1

1381861-91-1 structure

Name: Bromo-PEG2-C2-Boc
Chemical Name: Bromo-PEG2-t-butyl ester
CAS Number: 1381861-91-1
Molecular Formula: C₁₁H₂₁BrO₄
Molecular Weight: 297.18604
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-10-14 19:04:39
Modify Date: 2025-08-26 12:39:09
Bromo-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Bromo-PEG2-t-butyl ester
Synonyms	Bromo-PEG3-t-butyl ester

Description	Bromo-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562