Bromo-PEG2-C2-Boc

Modify Date: 2024-01-09 21:27:27

Bromo-PEG2-C2-Boc Structure
Bromo-PEG2-C2-Boc structure
Common Name Bromo-PEG2-C2-Boc
CAS Number 1381861-91-1 Molecular Weight 297.18604
Density 1.240±0.06 g/cm3 Boiling Point 332.0±22.0 °C
Molecular Formula C11H21BrO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromo-PEG2-C2-Boc


Bromo-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bromo-PEG2-t-butyl ester
Synonym More Synonyms

 Bromo-PEG2-C2-Boc Biological Activity

Description Bromo-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.240±0.06 g/cm3
Boiling Point 332.0±22.0 °C
Molecular Formula C11H21BrO4
Molecular Weight 297.18604

 Synonyms

Bromo-PEG3-t-butyl ester