Name | 2-(Azido-PEG2-amido)-1,3-propandiol |
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Synonyms |
MFCD22574770
Propanamide, 3-[2-(2-azidoethoxy)ethoxy]-N-[2-hydroxy-1-(hydroxymethyl)ethyl]- 3-[2-(2-Azidoethoxy)ethoxy]-N-(1,3-dihydroxy-2-propanyl)propanamide |
Description | 2-(Azido-PEG2-amido)-13-propandiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
Target |
PEGs |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Molecular Formula | C10H20N4O5 |
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Molecular Weight | 276.290 |
Exact Mass | 276.143372 |
LogP | -1.82 |