2-(Azido-PEG2-amido)-1,3-propandiol

Modify Date: 2024-01-02 18:18:48

2-(Azido-PEG2-amido)-1,3-propandiol structure	Common Name	2-(Azido-PEG2-amido)-1,3-propandiol
	CAS Number	1398044-52-4	Molecular Weight	276.290
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₀H₂₀N₄O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2-(Azido-PEG2-amido)-1,3-propandiol

2-(Azido-PEG2-amido)-13-propandiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-(Azido-PEG2-amido)-1,3-propandiol
Synonym	More Synonyms

Description	2-(Azido-PEG2-amido)-13-propandiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

MFCD22574770

Propanamide, 3-[2-(2-azidoethoxy)ethoxy]-N-[2-hydroxy-1-(hydroxymethyl)ethyl]-

3-[2-(2-Azidoethoxy)ethoxy]-N-(1,3-dihydroxy-2-propanyl)propanamide

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