1442106-10-6
1442106-10-6 structure
- Name: MM-401
- Chemical Name: MM-401
- CAS Number: 1442106-10-6
- Molecular Formula:
- Molecular Weight:
- Catalog: Signaling Pathways Epigenetics Histone Methyltransferase
- Create Date: 2018-06-03 01:58:04
- Modify Date: 2024-01-13 08:28:36
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MM-401 is a potent inhibitor for the MLL1-WDR5 interaction with the IC50 of 0.9 nM in disrupting WDR5-MLL1 interaction. MM-401 maintains high binding affinity to WDR5 (Ki<1 nM). MM-401 specifically inhibits MLL1 H3 lysine (K) 4 methyltransferase activity but does not affect other MLL family histone methyltransferases (HMTs). MM-401 can be used for the research of MLL leukemia[1].
| Name | MM-401 |
|---|---|
| Synonyms | MM401 |
| Description | MM-401 is a potent inhibitor for the MLL1-WDR5 interaction with the IC50 of 0.9 nM in disrupting WDR5-MLL1 interaction. MM-401 maintains high binding affinity to WDR5 (Ki<1 nM). MM-401 specifically inhibits MLL1 H3 lysine (K) 4 methyltransferase activity but does not affect other MLL family histone methyltransferases (HMTs). MM-401 can be used for the research of MLL leukemia[1]. |
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| No Any Chemical & Physical Properties |