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1446282-44-5

1446282-44-5 structure
1446282-44-5 structure
  • Name: Bromo-PEG2-phosphonic acid
  • Chemical Name: Bromo-PEG2-phosphonic acid
  • CAS Number: 1446282-44-5
  • Molecular Formula: C6H14BrO5P
  • Molecular Weight: 277.05
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-21 18:45:57
  • Modify Date: 2024-01-09 16:25:46
  • Bromo-PEG2-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bromo-PEG2-phosphonic acid
Synonyms MFCD25424120
Description Bromo-PEG2-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C6H14BrO5P
Molecular Weight 277.05