Bromo-PEG2-phosphonic acid

Modify Date: 2024-01-09 16:25:46

Bromo-PEG2-phosphonic acid Structure
Bromo-PEG2-phosphonic acid structure
Common Name Bromo-PEG2-phosphonic acid
CAS Number 1446282-44-5 Molecular Weight 277.05
Density N/A Boiling Point N/A
Molecular Formula C6H14BrO5P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bromo-PEG2-phosphonic acid


Bromo-PEG2-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bromo-PEG2-phosphonic acid
Synonym More Synonyms

 Bromo-PEG2-phosphonic acid Biological Activity

Description Bromo-PEG2-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C6H14BrO5P
Molecular Weight 277.05

 Synonyms

MFCD25424120