157938-23-3

157938-23-3 structure

Name: pTH (1-31) (human)
Chemical Name: PTH (1-31) (HUMAN)
CAS Number: 157938-23-3
Molecular Formula: C₁₆₂H₂₆₉N₄₉O₄₇S₂
Molecular Weight:
Catalog: Research Areas Metabolic Disease
Create Date: 2018-07-05 03:40:48
Modify Date: 2024-01-12 16:07:41
Human PTH-(1-31) is the 1-31 fragment of human PTH. Human PTH-(1-31) stimulates the release of cAMP and also is a weaker stimulator of the 25-hydroxyvitamin D-1α-hydroxylase. Human PTH-(1-31) induces bone formation without inducing bone resorption. Human PTH-(1-31) has the potential for the research of osteoporosis[1][2].

Name	PTH (1-31) (HUMAN)
Synonyms	PTH (1-31) (HUMAN)

Description	Human PTH-(1-31) is the 1-31 fragment of human PTH. Human PTH-(1-31) stimulates the release of cAMP and also is a weaker stimulator of the 25-hydroxyvitamin D-1α-hydroxylase. Human PTH-(1-31) induces bone formation without inducing bone resorption. Human PTH-(1-31) has the potential for the research of osteoporosis[1][2].
Related Catalog	Signaling Pathways >> Others >> Thyroid Hormone Receptor Research Areas >> Metabolic Disease
References	[1]. Fraher LJ, et al. Comparison of the biochemical responses to human parathyroid hormone-(1-31)NH2 and hPTH-(1-34) in healthy humans. J Clin Endocrinol Metab. 1999 Aug;84(8):2739-43. [2]. K. Henriksen, et al. Evaluation of the efficacy, safety and pharmacokinetic profile of oral recombinant human parathyroid hormone [rhPTH(1-31)NH2] in postmenopausal women with osteoporosis. Bone. 2013, 53 (1): 160-166.

Molecular Formula	C₁₆₂H₂₆₉N₄₉O₄₇S₂
Storage condition	-15°C