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174569-25-6

174569-25-6 structure
174569-25-6 structure
  • Name: m-PEGn-NHS ester
  • Chemical Name: Methoxy-PEG-propionicacid-N-succinimidylester
  • CAS Number: 174569-25-6
  • Molecular Formula: (C2H4O)nC8H11NO5
  • Molecular Weight: 1787.0688
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-11-09 18:41:35
  • Modify Date: 2024-02-25 17:17:18
  • m-PEGn-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Methoxy-PEG-propionicacid-N-succinimidylester
Description m-PEGn-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Molecular Formula (C2H4O)nC8H11NO5
Molecular Weight 1787.0688