1800414-71-4

1800414-71-4 structure

Name: Azido-PEG11-amine
Chemical Name: Azido-PEG11-amine
CAS Number: 1800414-71-4
Molecular Formula: C₂₄H₅₀N₄O₁₁
Molecular Weight: 570.674
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2019-01-21 18:59:34
Modify Date: 2024-01-02 14:02:55
Azido-PEG11-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Azido-PEG11-amine
Synonyms	35-Azido-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontan-1-amine Azido-dPEG(R)11-amine 3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontan-1-amine, 35-azido- MFCD08274605

Description	Azido-PEG11-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562