Azido-PEG11-amine

Modify Date: 2024-01-02 14:02:55

Azido-PEG11-amine Structure
Azido-PEG11-amine structure
Common Name Azido-PEG11-amine
CAS Number 1800414-71-4 Molecular Weight 570.674
Density N/A Boiling Point N/A
Molecular Formula C24H50N4O11 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG11-amine


Azido-PEG11-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG11-amine
Synonym More Synonyms

 Azido-PEG11-amine Biological Activity

Description Azido-PEG11-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C24H50N4O11
Molecular Weight 570.674
Exact Mass 570.347595
LogP -3.95

 Synonyms

35-Azido-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontan-1-amine
Azido-dPEG(R)11-amine
3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontan-1-amine, 35-azido-
MFCD08274605
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