1802086-23-2

1802086-23-2 structure

Name: (Gly22)-Amyloid β-Protein (1-42)
Chemical Name: (Gly22)-Amyloid β-Protein (1-42)
CAS Number: 1802086-23-2
Molecular Formula: C₂₀₀H₃₀₇N₅₅O₅₈S
Molecular Weight:
Catalog: Research Areas Neurological Disease
Create Date: 2018-06-23 14:41:56
Modify Date: 2024-01-03 21:43:53
(Gly22)-Amyloid β-Protein (1-42) is a peptide fragment of amyloid β-protein (Aβ). Amyloid β-protein is the primary component of both vascular and parenchymal amyloid deposits in Alzheimer's disease. Mutation of Glu22 to Gly22 in Aβ can increase aggregation[1][2].

Name	(Gly22)-Amyloid β-Protein (1-42)
Synonyms	(GLY22)-AMYLOID Β-PROTEIN (1-42)

Description	(Gly22)-Amyloid β-Protein (1-42) is a peptide fragment of amyloid β-protein (Aβ). Amyloid β-protein is the primary component of both vascular and parenchymal amyloid deposits in Alzheimer's disease. Mutation of Glu22 to Gly22 in Aβ can increase aggregation[1][2].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Poduslo JF, et al. Receptor-mediated transport of human amyloid beta-protein 1-40 and 1-42 at the blood-brain barrier. Neurobiol Dis. 1999 Jun;6(3):190-9. [2]. Xiaoling Lin, et al. Identification of novel oligopeptides from the simulated digestion of sea cucumber (Stichopus japonicus) to alleviate Aβ aggregation progression. Journal of Functional Foods. Volume 60, September 2019, 103412

Molecular Formula	C₂₀₀H₃₀₇N₅₅O₅₈S