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1818294-27-7

1818294-27-7 structure
1818294-27-7 structure
  • Name: S-acetyl-PEG3-Boc
  • Chemical Name: S-acetyl-PEG3-t-butyl ester
  • CAS Number: 1818294-27-7
  • Molecular Formula: C15H28O6S
  • Molecular Weight: 336.444
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-21 13:11:16
  • Modify Date: 2024-01-09 09:09:05
  • S-acetyl-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name S-acetyl-PEG3-t-butyl ester
Synonyms 2-Methyl-2-propanyl 2-oxo-6,9,12-trioxa-3-thiapentadecan-15-oate
MFCD22574782
6,9,12-Trioxa-3-thiapentadecan-15-oic acid, 2-oxo-, 1,1-dimethylethyl ester
Description S-acetyl-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.1±0.1 g/cm3
Boiling Point 413.9±35.0 °C at 760 mmHg
Molecular Formula C15H28O6S
Molecular Weight 336.444
Flash Point 188.4±14.0 °C
Exact Mass 336.160645
LogP 1.52
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.471
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