Name | Fmoc-PEG6-NHS ester |
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Synonyms |
MFCD24539479
9H-Fluoren-9-ylmethyl {21-[(2,5-dioxo-1-pyrrolidinyl)oxy]-21-oxo-3,6,9,12,15,18-hexaoxahenicos-1-yl}carbamate Carbamic acid, N-[21-[(2,5-dioxo-1-pyrrolidinyl)oxy]-21-oxo-3,6,9,12,15,18-hexaoxaheneicos-1-yl]-, 9H-fluoren-9-ylmethyl ester |
Description | Fmoc-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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Related Catalog | |
Target |
PEGs Alkyl/ether |
In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
References |
Density | 1.3±0.1 g/cm3 |
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Molecular Formula | C34H44N2O12 |
Molecular Weight | 672.719 |
Exact Mass | 672.289429 |
LogP | 0.06 |
Index of Refraction | 1.575 |
Storage condition | 2-8°C |