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2086688-99-3

2086688-99-3 structure
2086688-99-3 structure
  • Name: Acid-PEG2-C2-Boc
  • Chemical Name: Acid-PEG2-t-butyl ester
  • CAS Number: 2086688-99-3
  • Molecular Formula: C12H22O6
  • Molecular Weight: 262.3
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-18 00:25:01
  • Modify Date: 2024-02-04 17:54:35
  • Acid-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Acid-PEG2-t-butyl ester
Synonyms MFCD30723272
Description Acid-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C12H22O6
Molecular Weight 262.3