Acid-PEG2-C2-Boc

Modify Date: 2024-02-04 17:54:35

Acid-PEG2-C2-Boc Structure
Acid-PEG2-C2-Boc structure
Common Name Acid-PEG2-C2-Boc
CAS Number 2086688-99-3 Molecular Weight 262.3
Density N/A Boiling Point N/A
Molecular Formula C12H22O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Acid-PEG2-C2-Boc


Acid-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Acid-PEG2-t-butyl ester
Synonym More Synonyms

 Acid-PEG2-C2-Boc Biological Activity

Description Acid-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C12H22O6
Molecular Weight 262.3

 Synonyms

MFCD30723272