Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Cyclo(RGDyK)
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: CYCLO(-ARG-GLY-ASP-D-TYR-LYS)
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

217099-14-4

217099-14-4 structure

217099-14-4 structure

Name: Cyclo(-Arg-Gly-Asp-D-Tyr-Lys) trifluoroacetate salt
Chemical Name: CYCLO(-ARG-GLY-ASP-D-TYR-LYS)
CAS Number: 217099-14-4
Molecular Formula: C₂₇H₄₁N₉O₈
Molecular Weight: 619.67
Catalog: Signaling Pathways Cytoskeleton Integrin
Create Date: 2018-07-19 17:26:14
Modify Date: 2025-08-20 16:43:49
Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM.

Name	CYCLO(-ARG-GLY-ASP-D-TYR-LYS)
Synonyms	CYCLO (RGDYK)

Description	Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cytoskeleton >> Integrin
Target	IC50: 20 nM (αVβ3 Integrin), 3000 nM (αIIbβ3 Integrin), 4000 nM (αVβ5 Integrin)[1]
In Vitro	Cyclo(RGDyK) (c(RGDyK(SAA)) shows high affinity and selectivity for αVβ3 over αVβ5 (IC50=4000 nM) and αIIbβ3 (IC50=3000 nM)[1].
References	[1]. Haubner R, et al. Glycosylated RGD-containing peptides: tracer for tumor targeting and angiogenesis imaging with improved biokinetics. J Nucl Med. 2001 Feb;42(2):326-36.

Molecular Formula	C₂₇H₄₁N₉O₈
Molecular Weight	619.67

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