518044-49-0
518044-49-0 structure
- Name: Hydroxy-PEG3-acid
- Chemical Name: PEG4-acid
- CAS Number: 518044-49-0
- Molecular Formula: C9H18O6
- Molecular Weight: 266.288
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-11-29 22:38:26
- Modify Date: 2024-01-12 09:16:00
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Hydroxy-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | PEG4-acid |
|---|---|
| Synonyms |
MFCD22574805
1-Hydroxy-3,6,9,12-tetraoxapentadecan-15-oic acid 3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-hydroxy- |
| Description | Hydroxy-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1] |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 420.7±40.0 °C at 760 mmHg |
| Molecular Formula | C9H18O6 |
| Molecular Weight | 266.288 |
| Flash Point | 155.5±20.8 °C |
| Exact Mass | 266.136566 |
| LogP | -2.07 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
| Index of Refraction | 1.466 |
| Hazard Codes | Xi |
|---|