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596820-83-6

596820-83-6 structure
596820-83-6 structure
  • Name: Biotin-PEG2-NHS ester
  • Chemical Name: 9-biotinlaMino-4,7-dioxanonanoic acid N-hydroxysucciniMidyl ester
  • CAS Number: 596820-83-6
  • Molecular Formula: C21H32N4O8S
  • Molecular Weight: 500.56578
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-10-17 10:27:36
  • Modify Date: 2024-01-12 19:06:28
  • Biotin-PEG2-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 9-biotinlaMino-4,7-dioxanonanoic acid N-hydroxysucciniMidyl ester
Description Biotin-PEG2-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

Molecular Formula C21H32N4O8S
Molecular Weight 500.56578