DC Chemicals Limited
China
Product Name: ITMN 4077
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: ITMN 4077
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

790305-05-4

790305-05-4 structure

790305-05-4 structure

Name: ITMN 4077
Chemical Name: ITMN 4077
CAS Number: 790305-05-4
Molecular Formula: C₂₆H₄₀N₄O₈S
Molecular Weight: 568.6828
Catalog: Signaling Pathways Metabolic Enzyme/Protease HCV Protease
Create Date: 2018-12-08 14:37:20
Modify Date: 2024-04-05 15:34:07
ITMN 4077 is a macrocyclic inhibitor against Hepatitis C Virus (HCV) NS3 protease (EC50: 2131 nM)[1][2].

Name	ITMN 4077

Description	ITMN 4077 is a macrocyclic inhibitor against Hepatitis C Virus (HCV) NS3 protease (EC50: 2131 nM)[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> HCV Protease
Target	HCV NS3 protease[2]
References	[1]. Rajagopalan R, et al. Inhibition and binding kinetics of the hepatitis C virus NS3 protease inhibitor ITMN-191 reveals tight binding and slow dissociative behavior. Biochemistry. 2009 Mar 24;48(11):2559-68. [2]. Jiang Y, et al. Discovery of danoprevir (ITMN-191/R7227), a highly selective and potent inhibitor of hepatitis C virus (HCV) NS3/4A protease. J Med Chem. 2014 Mar 13;57(5):1753-69.

Molecular Formula	C₂₆H₄₀N₄O₈S
Molecular Weight	568.6828