932741-18-9

932741-18-9 structure

Name: Propargyl-PEG3-azide
Chemical Name: Propargyl-PEG3-amine
CAS Number: 932741-18-9
Molecular Formula: C₉H₁₅N₃O₃
Molecular Weight: 213.234
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-07 15:11:22
Modify Date: 2024-01-09 20:32:35
Propargyl-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Propargyl-PEG3-amine
Synonyms	PROPARGYL-PEG3-NH2

Description	Propargyl-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562