Propargyl-PEG3-azide

Modify Date: 2024-01-09 20:32:35

Propargyl-PEG3-azide Structure
Propargyl-PEG3-azide structure
Common Name Propargyl-PEG3-azide
CAS Number 932741-18-9 Molecular Weight 213.234
Density N/A Boiling Point N/A
Molecular Formula C9H15N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Propargyl-PEG3-azide


Propargyl-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Propargyl-PEG3-amine
Synonym More Synonyms

 Propargyl-PEG3-azide Biological Activity

Description Propargyl-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C9H15N3O3
Molecular Weight 213.234
Exact Mass 213.111343
LogP 0.04

 Synonyms

PROPARGYL-PEG3-NH2