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98627-70-4

98627-70-4 structure
98627-70-4 structure
  • Name: Bis-aminooxy-PEG3
  • Chemical Name: Bis-(Aminoxy)-PEG3
  • CAS Number: 98627-70-4
  • Molecular Formula: C8H20N2O5
  • Molecular Weight: 224.25
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-06 08:58:15
  • Modify Date: 2024-01-09 14:37:37
  • Bis-aminooxy-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Bis-(Aminoxy)-PEG3
Synonyms BIS-(AMINOOXY)-PEG3
Description Bis-aminooxy-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C8H20N2O5
Molecular Weight 224.25