Bis-aminooxy-PEG3

Modify Date: 2024-01-09 14:37:37

Bis-aminooxy-PEG3 Structure
Bis-aminooxy-PEG3 structure
Common Name Bis-aminooxy-PEG3
CAS Number 98627-70-4 Molecular Weight 224.25
Density N/A Boiling Point N/A
Molecular Formula C8H20N2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bis-aminooxy-PEG3


Bis-aminooxy-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bis-(Aminoxy)-PEG3
Synonym More Synonyms

 Bis-aminooxy-PEG3 Biological Activity

Description Bis-aminooxy-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C8H20N2O5
Molecular Weight 224.25

 Synonyms

BIS-(AMINOOXY)-PEG3
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