1230628-71-3

1230628-71-3 structure

Name: ML132
Chemical Name: ML-132
CAS Number: 1230628-71-3
Molecular Formula: C₂₂H₂₈ClN₅O₅
Molecular Weight: 477.9
Catalog: Signaling Pathways Apoptosis Caspase
Create Date: 2018-06-14 23:03:15
Modify Date: 2026-07-01 12:13:29
ML132 (NCGC 00185682) is a potent and selective caspase 1 inhibitor with an IC50 of 0.316 nM.

Name	ML-132

Description	ML132 (NCGC 00185682) is a potent and selective caspase 1 inhibitor with an IC50 of 0.316 nM.
Related Catalog	Signaling Pathways >> Apoptosis >> Caspase Research Areas >> Cancer
Target	IC50: 0.316 nM (Caspase 1)[1]
References	[1]. Boxer MB, et al. A highly potent and selective caspase 1 inhibitor that utilizes a key 3-cyanopropanoic acid moiety. ChemMedChem. 2010 May 3;5(5):730-8.