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1353011-89-8

1353011-89-8 structure
1353011-89-8 structure
  • Name: DNP-NH-PEG2-C2-acid
  • Chemical Name: DNP-PEG2-acid
  • CAS Number: 1353011-89-8
  • Molecular Formula: C13H17N3O8
  • Molecular Weight: 343.289
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-02 16:50:40
  • Modify Date: 2024-01-16 21:24:06
  • DNP-NH-PEG2-C2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

Name DNP-PEG2-acid
Synonyms MFCD20926369
3-(2-{2-[(2,4-Dinitrophenyl)amino]ethoxy}ethoxy)propanoic acid
Propanoic acid, 3-[2-[2-[(2,4-dinitrophenyl)amino]ethoxy]ethoxy]-
Description DNP-NH-PEG2-C2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density 1.4±0.1 g/cm3
Boiling Point 573.7±50.0 °C at 760 mmHg
Molecular Formula C13H17N3O8
Molecular Weight 343.289
Flash Point 300.8±30.1 °C
Exact Mass 343.101563
LogP 1.61
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.600
Hazard Codes Xi