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1374658-86-2

1374658-86-2 structure
1374658-86-2 structure
  • Name: Biotin-PEG3-C3-NH2
  • Chemical Name: Biotin-PEG3-(CH2)3-NH2
  • CAS Number: 1374658-86-2
  • Molecular Formula: C20H38N4O5S
  • Molecular Weight: 446.6
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-23 06:43:17
  • Modify Date: 2024-01-16 18:02:43
  • Biotin-PEG3-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Biotin-PEG3-(CH2)3-NH2
Description Biotin-PEG3-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C20H38N4O5S
Molecular Weight 446.6