Biotin-PEG3-C3-NH2

Modify Date: 2025-09-10 15:25:34

Biotin-PEG3-C3-NH2 Structure
Biotin-PEG3-C3-NH2 structure
Common Name Biotin-PEG3-C3-NH2
CAS Number 1374658-86-2 Molecular Weight 446.6
Density N/A Boiling Point N/A
Molecular Formula C20H38N4O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotin-PEG3-C3-NH2


Biotin-PEG3-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Biotin-PEG3-(CH2)3-NH2

 Biotin-PEG3-C3-NH2 Biological Activity

Description Biotin-PEG3-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C20H38N4O5S
Molecular Weight 446.6
InChIKey XNGTVIOREZIKAE-VBIIVCKISA-N
SMILES NCCCOCCOCCOCCCNC(=O)CCCCC1SCC2NC(=O)NC21
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