142864-19-5

142864-19-5 structure

Name: Enlimomab
Chemical Name: Enlimomab
CAS Number: 142864-19-5
Molecular Formula:
Molecular Weight:
Catalog: Signaling Pathways Cytoskeleton Integrin
Create Date: 2018-11-09 10:45:45
Modify Date: 2024-01-03 14:28:48
Enlimomab (BI-RR 0001), a murine IgG2a monoclonal antibody to the human ICAM-1, inhibits leukocyte adhesion to the vascular endothelium, thereby decreasing leukocyte extravasation and inflammatory tissue injury. Enlimomab has anti-inflammatory effects, and can be used for stroke research[1] [2] .

Name	Enlimomab

Description	Enlimomab (BI-RR 0001), a murine IgG2a monoclonal antibody to the human ICAM-1, inhibits leukocyte adhesion to the vascular endothelium, thereby decreasing leukocyte extravasation and inflammatory tissue injury. Enlimomab has anti-inflammatory effects, and can be used for stroke research[1] [2] .
Related Catalog	Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease Signaling Pathways >> Cytoskeleton >> Integrin
In Vitro	在全血中，Enlimomab 以补体依赖的方式激活静息中性粒细胞[1]。
References	[1]. J Vuorte, et al. Anti-ICAM-1 monoclonal antibody R6.5 (Enlimomab) promotes activation of neutrophils in whole blood. J Immunol. 1999 Feb 15;162(4):2353-7. [2]. [2]Gregory J del Zoppo. Acute anti-inflammatory approaches to ischemic stroke. Ann N Y Acad Sci. 2010 Oct;1207:143-8.

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