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1446282-17-2

1446282-17-2 structure
1446282-17-2 structure
  • Name: Diethoxy-phosphorylethyl-PEG5-ethylphosphonic acid
  • Chemical Name: Diethoxy-phosphorylethyl-PEG5-ethylphosphonic acid
  • CAS Number: 1446282-17-2
  • Molecular Formula: C16H36O11P2
  • Molecular Weight: 466.4
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-07 16:42:27
  • Modify Date: 2024-01-29 14:51:35
  • Diethoxy-phosphorylethyl-PEG5-ethylphosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Diethoxy-phosphorylethyl-PEG5-ethylphosphonic acid
Synonyms MFCD25424119
Description Diethoxy-phosphorylethyl-PEG5-ethylphosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C16H36O11P2
Molecular Weight 466.4
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