Diethoxy-phosphorylethyl-PEG5-ethylphosphonic acid

Modify Date: 2024-01-29 14:51:35

Diethoxy-phosphorylethyl-PEG5-ethylphosphonic acid Structure
Diethoxy-phosphorylethyl-PEG5-ethylphosphonic acid structure
Common Name Diethoxy-phosphorylethyl-PEG5-ethylphosphonic acid
CAS Number 1446282-17-2 Molecular Weight 466.4
Density N/A Boiling Point N/A
Molecular Formula C16H36O11P2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Diethoxy-phosphorylethyl-PEG5-ethylphosphonic acid


Diethoxy-phosphorylethyl-PEG5-ethylphosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Diethoxy-phosphorylethyl-PEG5-ethylphosphonic acid
Synonym More Synonyms

  Biological Activity

Description Diethoxy-phosphorylethyl-PEG5-ethylphosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C16H36O11P2
Molecular Weight 466.4

 Synonyms

MFCD25424119