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1446282-34-3

1446282-34-3 structure
1446282-34-3 structure
  • Name: TFP-PEG3-TFP
  • Chemical Name: TFP-PEG3-TFP
  • CAS Number: 1446282-34-3
  • Molecular Formula: C22H18F8O7
  • Molecular Weight: 546.36
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-07-03 10:36:49
  • Modify Date: 2024-01-06 18:21:27
  • TFP-PEG3-TFP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name TFP-PEG3-TFP
Synonyms BIS-PEG3-TFP ESTER
Description TFP-PEG3-TFP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C22H18F8O7
Molecular Weight 546.36