TFP-PEG3-TFP

Modify Date: 2024-01-06 18:21:27

TFP-PEG3-TFP Structure
TFP-PEG3-TFP structure
Common Name TFP-PEG3-TFP
CAS Number 1446282-34-3 Molecular Weight 546.36
Density N/A Boiling Point N/A
Molecular Formula C22H18F8O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TFP-PEG3-TFP


TFP-PEG3-TFP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name TFP-PEG3-TFP
Synonym More Synonyms

 TFP-PEG3-TFP Biological Activity

Description TFP-PEG3-TFP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C22H18F8O7
Molecular Weight 546.36

 Synonyms

BIS-PEG3-TFP ESTER