1449566-36-2

1449566-36-2 structure

Name: RS 09
Chemical Name: RS 09
CAS Number: 1449566-36-2
Molecular Formula: C₃₁H₄₉N₉O₉
Molecular Weight: 691.776
Catalog: Signaling Pathways Immunology/Inflammation Toll-like Receptor (TLR)
Create Date: 2018-06-15 21:53:51
Modify Date: 2024-01-09 12:47:00
RS 09 is a TLR4 agonist. RS 09 promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. RS 09 acts as an adjuvant in vivo; RS 09 enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.

Name	RS 09
Synonyms	L-Alanyl-L-prolyl-L-prolyl-L-histidyl-L-alanyl-L-leucyl-L-serine L-Serine, L-alanyl-L-prolyl-L-prolyl-L-histidyl-L-alanyl-L-leucyl- MFCD30182368

Description	RS 09 is a TLR4 agonist. RS 09 promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. RS 09 acts as an adjuvant in vivo; RS 09 enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Inflammation/Immunology
References	[1]. Arulkumaran Shanmugam,et al. Synthetic Toll Like receptor-4 (TLR-4) Agonist Peptides as a Novel Class of Adjuvants. PLoS One. 2012;7(2):e30839.