146551-23-7
146551-23-7 structure
- Name: Mal-PEG3-alcohol
- Chemical Name: Mal-PEG3-alcohol
- CAS Number: 146551-23-7
- Molecular Formula: C10H15NO5
- Molecular Weight: 229.230
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-14 02:39:43
- Modify Date: 2024-03-02 14:20:29
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Mal-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Mal-PEG3-alcohol |
|---|---|
| Synonyms |
8-(N-maleimidyl)-3,6-dioxaoctan-1-ol
1H-Pyrrole-2,5-dione, 1-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]- 1-{2-[2-(2-Hydroxyethoxy)ethoxy]ethyl}-1H-pyrrole-2,5-dione |
| Description | Mal-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 393.8±27.0 °C at 760 mmHg |
| Molecular Formula | C10H15NO5 |
| Molecular Weight | 229.230 |
| Flash Point | 192.0±23.7 °C |
| Exact Mass | 229.095016 |
| LogP | -1.25 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.521 |